Background: Pre-eclampsia (PE) is a pregnancy specific disorder and a major cause of both fetal and maternal morbidity and mortality worldwide. The Aim of this study was to identify risk factors and pregnancy outcomes among pregnant women with pre-eclampsia. Research design: An exploratory descriptive design was used. Sample:A purposive of 200 women who were selected randomly. Setting: from labor unit affiliated to Damanhour Medical National Institute. Tools: three tools were used to collect data. The first tool was a structured interview questionnaire. The second tool: assessment of women's knowledge regarding pre-eclampsia and the third tool pregnancy outcome assessment checklist. Results: Premature rupture of membranes was observed among approximately three- quarters of them. More than half of them had caesarean section labor. Fetal distress was observed among about one-third of them and low birth weight (1500-2400 gm) constituted 27.6% of study subjects. Furthermore, admission to neonatal intensive care unit and oxygen administration were needed for (23 % & 36.8%) of study subjects' neonates respectively. Also, positive significant correlations were observed between pre-eclampsia and age, education, residence, parity as well as number of antenatal visit. In addition 69.0% of study subjects had poor total score. The study concluded that, age, level of education, residence, parity, and antenatal visits were determinants risk factors of pre-eclampsia in which that was significantly associated with maternal and neonatal morbidities as well as increasing cesarean section, LBW, and birth asphyxia. Consequently, it is recommended that teaching programs should be conducted to identify mothers at risk and encourage them for proper antenatal care.