Background; good nutrition & eating are important especially during treatment which might enhance the effectiveness of tumor treatments & which can lead to better outcomes for cancer treatment. The aim: assess Knowledge, attitude, and practices regarding nutrition for patients with chemotherapy. Samples: A convenience sample of 60 adult patients, the age between 20 - 60 years both sex, evidence of cancer and recent receiving all types of chemotherapy. Three tools were utilized for data collection were Tool (I) Structured interviewing Questionnaire Tool (II) Nutritional Status Assessment and Tool (III) Chemotherapy Knowledge, Attitude and practice (KAP) Questionnaire. Results: More than two thirds of samples were unsatisfied level of knowledge (60%). The majority of studied sample were positive attitude and poor practice (95%, 86.6%) respectively. Conclusions: About two third of the patient were unsatisfactory information. The majority of the patient were positive attitude and had poor practice respectively. Recommendations: Give advices & guidelines for patients to minimize malnutrition complications & improve clinical outcomes, formulate nutritional assessment form or sheet to be suitable for Egyptian patients undergoing chemotherapy in the hospitals.