Rheumatoid arthritis (RA) is the most common inflammatory polyarthritis It can cause persistent joint pain, joint damage and long-term disability (especially in the hands and feet).The goals of management are to prevent or control joint damage, maximize function and decrease pain. Methods: The study was conducted in the Rheumatology department and outpatient clinic at Assiut university hospital, sample including Fifty female patients with RA, divided in two equal groups. Used The Health Assessment Questionnaire (HAQ), The Foot & Ankle Disability Index (FADI) and Michigan Hand outcome Questionnaire to collected of data. The study showed that there were highly significant statistical improvement (p < 0.001) regarding knowledge, total scores of common daily activity in both groups ( z ≤ 2.58 **) , foot and ankle functional status and ADL (z ≤ 2.58 **) and regarding to over hand function , and hand grip strength .Conclusion: based on the finding of the study might be improve treatment in RA by manipulation of education program regarding medication, nutritional counseling and physical exercises. Recommendations: Establishment specialized exercises program for patients with RA should be mainly included in treatment course