Aims of this study; Develop nursing care standards for venous thromboembolism for patient with orthopedic surgery. Subjects and method; Descriptive exploratory research design were utilized to conduct this study. This study was conducted in the Trauma Unit at Assiut University Hospital. The study sample of all available nurses 30 working in Internal Trauma Unit who were willing to participate in the study, in addition to patients 30 who had performed orthopedic surgery. Tools; nurses knowledge questionnaire sheet, nurses practice observation checklist sheet, basic nurse's opinionnaire sheet and patient assessment sheet. Results; Showed that; all of nurses had poor knowledge regarding nursing care standard of venous thromboembolism in orthopedic surgery patients and inadequacy in their practice. Majority of patient with pelvic fracture, lower limb fracture, repair of open fracture femur and hip fracture. Conclusion; All nurses had poor knowledge and inadequacy in their practice about nursing care standard of venous thromboembolism in orthopedic surgery patient. Recommendation; Application of the nursing care standards for venous thromboembolism in orthopedic surgery patients in service training program for nurses is important in trauma unit