Background: Improper disposal of household wastes cause health problem to the people from this problem irritation in eye, gastrointestinal problem, headache and allergies...etc. Aim of study: evaluate effect of household wastes on individuals health in rural villages at Assiut Governorate through assessing participant's knowledge, attitude and behavior about household waste disposal. Subjects and Method: Study conducted in Elwaan and Elmashiaa villages at Assiut Governorate. Descriptive research was used in the study. Tools composed of, first part socio-economic scale, second part knowledge questionnaire about waste disposal, third part attitude rating scale about waste disposal, fourth part behaviors questionnaire about waste disposal and fifth part effect of wastes on health. Results: findings of the study revealed that diarrhea and eye diseases are the most common disease caused by wastes followed by skin diseases, parasitic disease, dysentery, typhoid fever, scorpion bites, poisoning, hepatitis A virus (HAV) and snakes bites. It was clear that (61.2%) of participants had poor behavior. Conclusion: there were relation between poor wastes disposal and diseases and relation between caring with animals and birds in the house and diseases. Recommendations: health education program to the public about solid waste and its related issues through mass media.