Introduction and research problem: Medication errors in hospitals are very common and it caused huge trouble in community, So, the present study aimed to: Identify nurse perceptions about the Culture of Reporting medication error in Taif –hospitals. Research methodology: Across –sectional descriptive survey, a total of 150 nurses, in multiple settings, both, King Faisal, 68(45.3%) , Abdul-Aziz,37(24.7%) and Pediatric hospital,45(30%), at Taif City.Tool of data collection Structured interview questionnaire was used and composed of two parts. The first part was related to demographic data, aged, sex, working position, level of education and the second part was a Survey to seek Information about the reporting of medication errors, which is designed by Allina Hospitals, 2002. Results: Participants age ranged between 22 and 59 years old with Mean ±SD (30.24+_8.10)years ,the majority is diploma degree, staff nurse and female,( 74.3 %, 85.3% and 73.3%,respectively ),their experience ranged between 1-36 with means and SD ,( 6.76 &+_7.03)years. Also majority of participants strongly agree regarding use of new technology , good leadership and blame-free reporting ,have a vital role in preventing medication error. Conclusion: Reporting errors in a clear and transparent with no blame in workplace, decreasing workloads, applying quality standards, informatics technology and selecting qualified health personnel are the suitable solution for reducing medication errors. Recommendations: Preparing an educational training course for documenting and reporting system through utilization of information technology and quality standards in medication administration according to hospital police