We show valid non-traditional feedstuffs in broiler diets. Arbor Acres plus unsexed one-day old broiler chicks (n = 250) were used to study the effect of rice gluten meal (RGM) on growth performance, carcass characteristics, some serum biochemical parameters and economic efficiency as an alternative to soybean meal and corn gluten meal. They were randomly assigned to five treatments with five replicates per treatment (fifty chicks/ treatment; ten chicks/replicate). The experimental chicks were fed with isoenergetic and isonitrogenous diets supplemented with 0 (control), 3, 6, 9 and 12% RGM for 6 weeks. Growth performance parameters were monitored weekly. Five broilers from each treatment were slaughtered on day 42, for measuring the weight percentages of carcass dressing and internal organs. At 42 days of age, blood samples were collected and serum was separated for determination of serum lipid profile, glucose, total protein, albumin, and globulin. Results showed that broilers fed RGM (up to 12%) had the same performance parameters like the control diet and there was no significant alter among the different groups. RGM had no effect on dressing percentage and internal organs among treatments. Also, no significant change in the serum glucose, total cholesterol, triglycerides, HDL, LDL, total protein, albumin, globulin, ALT, AST, creatinine, uric acid and urea in dietary groups fed on diets contained RGM. The total returns (TR) and net profit revealed no significant (P>0.05) variation was recorded between the dietary groups. In conclusion, broilers fed the RGM diets compared well with those fed the control for growth performance, carcass dressing and blood metabolites and can be included in the broiler diet up to 12% without any deleterious impacts.