This study investigates safety and security measures from Egyptian hotel guests' viewpoint, through assessing the importance level and usage level of measuring and testing the gap between the importance and usage of measures. Using IPA Methodology, a stratified random sample was chosen. 500 questionnaires were randomly distributed to guests in 5-star hotels. The results indicated that the highly important and rarely usage measures are related to three dimensions; “Medical Preparedness, Guestroom Security, and Emergency Preparedness". Meanwhile, the less important and widely used measures are related to two dimensions; “Detectors, and Access Control".  Additionally, there is a statistically significant gap between the importance level and the usage level of measures.  Hence, there are opportunities for changes and improvements in Egyptian hotels.