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184731

Clinical and Laboratory Studies of Dermatophytosis Affected Dogs in Correlation to Oxidative Stress

Article

Last updated: 24 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Internal Medicine

Abstract

Skin diseases are one of the most common health problems in dogs. This study aimed to record the clinical and laboratory findings of dermatophytosis on dogs, with its effect on blood plasma as well as its correlation to oxidative stress.
The clinical study was conducted on two groups of dogs. The first group consisted of fourteen dogs that were clinically healthy and used as a control one.
The second group consisted of sixteen dogs at different ages affected and suffering from dermatophytosis.
All dogs were subjected to clinical examination followed by a special dermatological examination. Skin scrapings were examined under a light microscope for the detection of fungal spores. Blood samples were taken for hematological analysis and plasma samples for biochemical analysis.
Dermatophytosis affected dogs showed a highly significant decrease of hemoglobin, hematocrit, MCV values, and a significant decrease in RBCs count and MCHC as well as a highly significant increase in total leukocyte counts of diseased dogs when compared to control ones
Significant differences in hematological parameters were observed in dermatophytosis-affected dogs. Furthermore, Oxidative stress markers such as catalase, SOD, GPx, and MDA revealed significant variations in the diseased group when compared to healthy ones. A correlation between analyzed data revealed positive correlation between plasma zinc and copper levels and antioxidant enzymes as SOD, GPx in diseased dogs. 

DOI

10.21608/scvmj.2021.184731

Keywords

Dermatophytosis, hematological analysis, Oxidative stress markers, Correlation analysis

Authors

First Name

Thrwat

Last Name

Nafie

MiddleName

-

Affiliation

Department of internal medicine, Faculty of Vedterinary Medicine, Suez Canal University

Email

tnafie@hotmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Mahmoud

MiddleName

-

Affiliation

قسم طب الحيوان الامراض المعدية کلية الطب البيطرى جامعة قناة السويس الاسماعيلية

Email

mmostafa76@yahoo.com

City

-

Orcid

-

First Name

Dina

Last Name

Abdelkhalek

MiddleName

-

Affiliation

Department of Internal medicine, Faculty of Veterinary Medicine Suez Canal University, Ismailia

Email

dina_amin@vet.suez.edu.eg

City

-

Orcid

-

Volume

26

Article Issue

1

Related Issue

21781

Issue Date

2021-06-01

Receive Date

2021-02-03

Publish Date

2021-07-01

Page Start

17

Page End

26

Print ISSN

1110-6298

Online ISSN

2682-3284

Article File

SCVMJ_Volume 26_Issue 1_Pages 17-26.pdf

PDF . 818.8kB

Link

https://scvmj.journals.ekb.eg/article_184731.html

Detail API

https://scvmj.journals.ekb.eg/service?article_code=184731

Order

2

Type

Original Article

Type Code

992

Publication Type

Journal

Publication Title

Suez Canal Veterinary Medical Journal. SCVMJ

Publication Link

https://scvmj.journals.ekb.eg/

MainTitle

Clinical and Laboratory Studies of Dermatophytosis Affected Dogs in Correlation to Oxidative Stress

Details

Type

Article

Created At

22 Jan 2023