The present study was carried out to screen and analyze the characteristics of antibiotic resistance in Campylobacter strains isolated frompoultry and human in the poultry farms of different localities in Egypt. A total of 340 samples were taken from poultry and human from poultry farms and examined bacteriologically for isolation of Campylobacter organisms. Fifty-six (16.47%) samples were identified as Campylobacter-positive; 50 (14.71%) from poultry samples and 6(1.76%) from human samples using conventional method. The isolates were42 (12.35%) isolates for C. jejuni including 38 (12.67%) from poultry samples and4(10%) from human samples. Isolates for C. coli were 14 (4.12%) including 12 (4%) from poultry samples and 2 (5%) from human samples detected.  All Campylobacter isolates were evaluated for their antibiotic susceptibilities.
Results of Antibiogram revealed that Campylobacter isolates were resistant to one or more of the antibiotics tested. Resistance was most frequently observed against streptomycin (96.4%) amoxicillin (94.6%), doxycycline (87.5%), Ampicillin (83.9%), nalidixic acid (85.7%), erythromycin and ciprofloxacin (82.1%). C. jejuni strains were often resistant to cephalothin (35.7%) than C. coli strains (42.8%). C. coli were sensitive to erythromycin and Streptomycin (100%). C. jejuni was an increase sensitive to amoxicillin and streptomycin (95.2%). The trend of resistance to gentamicin (28.6%) and tetracycline (50%) was observed for C. jejuni.
The present study provides an assessment of the occurrence of multidrug resistance of Campylobacter isolates from chicken samples collected from the poultry farms in different localities in Egypt. The antimicrobial resistance rates among these pathogens are clearly important in risk assessment and management. Further research is also needed to better understand the relationship between antimicrobial used in poultry and humans and the bacterial resistance in humans.