The present study was carried out to investigate presence of edwardsiellosisin Sea bream Sparus aurata fished from Attaka fishing port, Suez-bay, Suez Governorate. 40 Fish S. aurata were collected randomly and freshly from Attaka fishing port during spring 2015. Naturally infected fish showed hemorrhages on different parts of body surface including fins and Gills cover, swollen abdomen with scales detachment. Isolation of the causative agent was performed from spleen, kidneys, liver and gills. Biochemical identification was performed using Microbact 24E which revealed 2 Edwardsiella tarda isolates (A and B).  Experimental infection by I/P route in Koi fish using (A), (B) isolates revealed 70 and 80% mortalities respectively. The LD50 was 2X10⁶ CFU/ml for (A) and (B) isolates. Histopathological examination on infected S. aurata showed necrosis and degeneration in gills, liver, kidneys and spleen.