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146598

The effects of weight loss intervention program on serum leptin level, histological and molecular alterations of adipose tissue in rat model with obesity.

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Last updated: 24 Dec 2024

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Abstract

Background: Obesity is a resilient and complex chronic disease.
Leptin is an adipocyte-derived hormone acts as a key regulator of feeding and energy expenditure.
The aim of our study was to assess the level of serum leptin as well as leptin immuno-histochemistry expression in adipose tissue in obese and non-obese rats.
Leptin was markedly detected in young preadipocytes during lipogenesis (before weight loss (regime) in contrast to adipocytes undergoing lipolysis (after weight loss (regime) in the later weak positive.
 
 

DOI

10.21608/blj.2020.146598

Authors

First Name

Nearmeen M.

Last Name

Rashad

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Affiliation

Internal Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

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First Name

Sally E.

Last Name

Sayed

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Affiliation

Biochemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt

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First Name

Mohamed H.

Last Name

Sherif

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-

Affiliation

Organic Chemistry Department, Faculty of Science Zagazig University, Zagazig, Egypt.

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First Name

Mahmoud Z.

Last Name

Sitohy

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-

Affiliation

Biochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig Egypt.

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Volume

16

Article Issue

1

Related Issue

21623

Issue Date

2020-12-01

Receive Date

2020-03-20

Publish Date

2020-12-01

Page Start

101

Page End

108

Print ISSN

1687-4773

Online ISSN

2974-4725

Article File

BLJ_Volume 16_Issue 1_Pages 101-108.pdf

PDF . 326.9kB

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https://blj.journals.ekb.eg/article_146598.html

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https://blj.journals.ekb.eg/service?article_code=146598

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Original Article

Type Code

988

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Journal

Publication Title

Biochemistry Letters

Publication Link

https://blj.journals.ekb.eg/

MainTitle

The effects of weight loss intervention program on serum leptin level, histological and molecular alterations of adipose tissue in rat model with obesity.

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Article

Created At

22 Jan 2023