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64446

EVALUATION OF ALPHA-GLUTATHIONE-S-TRANSFERASE AS A MARKER OF HEPATOCELLULAR DAMAGE

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Last updated: 24 Dec 2024

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Abstract

Alpha-glutathione-S-transferase (a-GST) are the cytoplasmatic class of enzymes responsible for cellular detoxifying processes. The serum a-GST activity in relation to chronic infection caused by hepatitis C virus (HCV) and acute infection caused by hepatitis A, B and C viruses. 15 anti-HCV negative and negative for HBV and HAV healthy subjects served (controls), 35 patients with chronic hepatitis [8/35 are anti-HCV positive subjects with normal alanine aminotransferases (ALT) and 27/35 chronic hepatitis are with high ALT levels]; 17 patients with acute liver disease (1 acute HCV infection, 3 acute HBV infections and 13 acute HAV infections were studied. Serum (a-GST) alpha glutathione-S-transferase, (aspartate aminotransferase, alkaline phosphatase (ALP), gamma glutamyl transferase GGT, total protein, albumin, total and direct bilirubin were assayed in all subjects, and after 0 week, 2 weeks and 4 weeks in the acute group.

DOI

10.21608/blj.2008.64446

Authors

First Name

Osman, H.

Last Name

Gh.

MiddleName

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Affiliation

Faculty of Science, Mansoura University.

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City

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Orcid

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First Name

Shiha,

Last Name

G. E

MiddleName

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Affiliation

Faculty of Medicine, Mansoura University

Email

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City

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Orcid

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First Name

El-Deeb,

Last Name

K.A.

MiddleName

-

Affiliation

Faculty of Science, Mansoura University

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-

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Volume

4

Article Issue

1

Related Issue

9740

Issue Date

2008-12-01

Receive Date

2008-02-04

Publish Date

2008-12-01

Page Start

15

Page End

40

Print ISSN

1687-4773

Online ISSN

2974-4725

Article File

BLJ_Volume 4_Issue 1_Pages 15-40.pdf

PDF . 420.7kB

Link

https://blj.journals.ekb.eg/article_64446.html

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https://blj.journals.ekb.eg/service?article_code=64446

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Original Article

Type Code

988

Publication Type

Journal

Publication Title

Biochemistry Letters

Publication Link

https://blj.journals.ekb.eg/

MainTitle

EVALUATION OF ALPHA-GLUTATHIONE-S-TRANSFERASE AS A MARKER OF HEPATOCELLULAR DAMAGE

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Article

Created At

22 Jan 2023