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63859

Aqueous extract of Costus Specious ameliorates the toxic effect of lead acetate on transcriptional factors of erythropioesis

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Last updated: 04 Jan 2025

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Abstract

   Background: The increase use of medicinal plants during last 5 years encourages us to study the possible effects of Coustus Speciosus.  Objective: In the present study, we tested the effect of Costus speciosus on the toxicity of Lead acetate.  Results: The results showed an increase of EPO and high expression levels of GATA-1 and FOG-1 while there is a low expressional level of SCF in animals treated with Costus speciosus.  Conclusion: Costus Specious has the ability to ameliorate the toxicity of lead acetate on erythropioesis. 

DOI

10.21608/blj.2014.63859

Keywords

Erythropioesis, erythropoietin, FOG-1, GATA-1, SCF

Authors

First Name

Yousef M.

Last Name

Shehata

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Affiliation

Professors of Biochemistry, Biochemistry Department, Faculty of Veterinary medicine, Zagazig University,44511, Zagazig, Egypt

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First Name

Mohamed F.

Last Name

Dowidar

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Professors of Biochemistry, Biochemistry Department, Faculty of Veterinary medicine, Zagazig University,44511, Zagazig, Egypt

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First Name

Haytham A.

Last Name

Ali

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Affiliation

Lecturers of Biochemistry, Biochemistry Department, Faculty of Veterinary medicine, Zagazig University, 44511, Zagazig, Egypt

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First Name

Aaser M.

Last Name

Abdelazim

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Affiliation

Lecturers of Biochemistry, Biochemistry Department, Faculty of Veterinary medicine, Zagazig University, 44511, Zagazig, Egypt

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First Name

Eman M.

Last Name

Elmogy

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-

Affiliation

3 Master of Biochemistry, Biochemistry Department, Faculty of Veterinary medicine, Zagazig University, 44511, Zagazig, Egypt

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Volume

10

Article Issue

1

Related Issue

9588

Issue Date

2014-12-01

Receive Date

2014-09-25

Publish Date

2014-12-01

Page Start

126

Page End

134

Print ISSN

1687-4773

Online ISSN

2974-4725

Article File

BLJ_Volume 10_Issue 1_Pages 126-134.pdf

PDF . 794.2kB

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https://blj.journals.ekb.eg/article_63859.html

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https://blj.journals.ekb.eg/service?article_code=63859

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10

Publication Type

Journal

Publication Title

Biochemistry Letters

Publication Link

https://blj.journals.ekb.eg/

MainTitle

Aqueous extract of Costus Specious ameliorates the toxic effect of lead acetate on transcriptional factors of erythropioesis

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Article

Created At

22 Jan 2023