This research aimed to test the relationship between employee empowerment and organizational citizenship behavior challenging dimension from the perspectives of Egyptian employees and to examine the role of proactive personality as a moderate variable. An online survey was used and data were collected from a sample of 490 respondents. Applying the structural equation modeling technique results revealed that, employee empowerment had no significant impact on change oriented OCB. Moreover, results indicated that proactive personality has a moderating effect on the relationships between employee empowerment and change-oriented OCB