Aim: The purpose of this study was to evaluate the efficacy of the (PRF) combined with collagen membrane in the management of gingival recession compared to the use of (PRF) alone. Subjects and methods: 10 sites including at least one tooth with Miller's class II or class III buccal/labial gingival recession defect after phase I therapy were divided randomly into 2 groups, Group (I) was treated with open flap surgery while using (PRF) and Group (II) was treated with open flap surgery while using (PRF) combined with collagen membrane. Clinical parameters were recorded at baseline, 3and 6 months postoperatively. Results: both treatment groups showed no significant root coverage, Probing sulcus depth (PSD) reduction, Clinical attachment level (CAL) gain 6-months after surgery when compared with baseline between two groups. However, there was a significant increase of Height of keratinized gingiva (HKG) between (Group I) and (Group II) at 3-months and 6-months. Conclusion: Both the treatment modalities proved to be effective techniques in treatment of root coverage and Using of PRF + Collagen membrane showed superior effect compared to PRF alone, suggest that PRF + Collagen membrane can provide additional benefits not in the treatment of gingival recession but in increasing of the width of attached gingiva