Aim: To compare, through cone-beam computed tomography (CBCT), the root resorption and treatment efficiency of two different mini-implant-assisted modalities in intruding the maxillary incisors. Subjects and Methods: The present study composed of 26 patients (males, females) aged between 12-18 years who had deep bite and elongated maxillary incisors. They were randomly selected and divided into two group: anterior mini-implant group (AMG) and posterior mini-implant group (PMG). In the AMG, approximately 40 g of force was applied per side with elastic chains and in the PMG, with beta-titanium wires. This study was conducted on CBCT scans taken before intrusion and after 18 weeks of intrusion. Result: The incisors showed a significant reduction in length and volume, this amount was greater in AMG than PMG. Significant changes in labial inclination of all incisors, which were greater in PMG than AMG. Conclusion: Posterior mini-implants assisted maxillary incisors intrusion is preferred than anterior mini-implant assisted maxillary incisor intrusion in case of upright position, as the use of such mechanics directs them to less root resorption and more labial tipping.