Beta
253870

Impact of the histological, biochemical, and cytogenetical changes caused by Ehrlich solid carcinoma (ESC) in the pregnant mice and treated with ethanolic extract of Tamarinds Indica seeds

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Biology and pharmaceutical sciences.

Abstract

All parts of Tamarinds indica plants are included in traditional medicine in India and other countries. There are many chemical values as phenolic materials that make it possess variable activities, most important of them antioxidant activity against cancer. The extract of Tamarinds Indica using to thwart various cancer types. Forty mice were divided into four groups; the first group was as control (normal mice), the second group was injected only with Ehrlich carcinoma cells, the third group was treated with Tamarinds indica extraction only, and the fourth group was injected with Ehrlich carcinoma cells and treated with Tamarinds indica extraction. At the final of the experiment, we represented the fourth group of mice has a significant reduction in cancer effects, which confirmed the anticancer activity of Tamarinds indica extraction in vivo (mice). Finally, the conclusion proves the efficacy of Tamarinds indica ethanolic extract as a cancer prophylactic chemotherapy in therapeutic approaches to treat cancer caused by Ehrlich cells in serum protein level, fetal tissues, cerebellum tissues, lung tissues, and chromosomes.

DOI

10.21608/ajbas.2022.147856.1112

Keywords

Ehrlich cells, Tamarinds Indica, mouse, histology, Cytogentics

Authors

First Name

Yasmin

Last Name

Abd El-Aziz

MiddleName

M.

Affiliation

Zoology Department, Faculty of Science, Port Said University, Port Said, Egypt.

Email

yasminabdelaziz2012@yahoo.com

City

Port Said

Orcid

-

First Name

Mariam

Last Name

Rashed

MiddleName

Y.

Affiliation

Zoology Department, Faculty of Science, Port-Said University, Egypt.

Email

mariamrashed2435@gmail.com

City

-

Orcid

-

First Name

Donia

Last Name

Agamy

MiddleName

W.

Affiliation

Zoology Department, Faculty of Science, Port-Said University, Egypt.

Email

doniawaleed099@gmail.com

City

-

Orcid

-

First Name

Hend

Last Name

Elmalaky

MiddleName

M.

Affiliation

Zoology Department, Faculty of Science, Port-Said University, Egypt.

Email

hendelmalaky5@gmail.com

City

-

Orcid

-

First Name

Rahma

Last Name

Abo-Elhamd

MiddleName

D.

Affiliation

Zoology Department, Faculty of Science, Port-Said University, Egypt.

Email

rahma.desokey@gmail.com

City

-

Orcid

-

First Name

Mariam

Last Name

Elsergany

MiddleName

M.

Affiliation

Zoology Department, Faculty of Science, Port-Said University, Egypt.

Email

maryamelsergany311@gmail.com

City

-

Orcid

-

First Name

Rahma

Last Name

Abdelhay

MiddleName

M.

Affiliation

Zoology Department, Faculty of Science, Port-Said University, Egypt.

Email

rahmaabdelhay5@gmail.com

City

-

Orcid

-

First Name

Ali

Last Name

Abu Almaaty

MiddleName

Hussein

Affiliation

Zoology Department, Faculty of Science, Port Said University

Email

ali_zoology_2010@yahoo.com

City

-

Orcid

-

Volume

4

Article Issue

1

Related Issue

38598

Issue Date

2023-01-01

Receive Date

2022-06-28

Publish Date

2023-01-01

Page Start

84

Page End

95

Online ISSN

2682-275X

Link

https://ajbas.journals.ekb.eg/article_253870.html

Detail API

https://ajbas.journals.ekb.eg/service?article_code=253870

Order

7

Type

Original Article

Type Code

947

Publication Type

Journal

Publication Title

Alfarama Journal of Basic & Applied Sciences

Publication Link

https://ajbas.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023