Autism spectrum disorder (ASD) is a huge public health problem in children all over the world. Autism is characterized by impairments in communication and social interaction, limited interests in activities, repetitive behaviors, and a diminished ability to perform in school, the workplace, and other aspects of life. In recent years, the estimated prevalence of autism spectrum diseases has risen considerably. The condition necessitates long-term therapy and is typically regarded as incurable. Pharmacological intervention, which includes psychiatric medicines to treat behavioral issues, is accompanied with considerable side effects. Behavioral therapy, education, and nutritional therapies are the basis of traditional management. It has been reported that using natural compounds along with the pharmacological medications have a positive effect in treating ASD youngsters, as well as diminishing the adverse effects of chemical medications. Unfortunately, there is a scarcity of data on the efficacy of natural remedies in ASD. The current review seeks to investigate studies of using natural remedies in ASD.