This study assesses the environmental aspects and air quality in chemical fertilizer industry. Misr Fertilizers Company (MOPCO) at Damietta, Egypt was used as a case study to monitor indoor and outdoor air emissions to find out the main source of air pollution and evaluate the air quality in the facility. MOPCO is located within the general free zone of Damietta Port and covers an area of 400,000 m² including three factories, three ammonia plants, and three urea production plants and a service area. Monitoring of carbon monoxide (CO), nitrogen dioxide (NO₂), ammonia (NH₃) and sulfur dioxide (SO₂) in addition to particulate matter (PM₁₀), noise and heat stress was carried out in the production units in MOPCO (e.g., filling area, ammonia pumping area, and boiler area (BFW) from January 2018 to July 2019. Outdoor air emissions were measured from the outlet stacks of granulation, reformer and the boiler at MOPCO. The obtained results from the three sites were less than the maximum permissible limits for CO (25 ppm), SO₂ (2 ppm), NO₂ (3 ppm), and NH₃ (25 ppm) according to Egyptian Environment Protection Low No. 4/1994 and its amendments (No. 9/2009). Detailed air dispersion modeling (AERMOD) was applied to determine the likelihood ground level concentrations resulting from the outdoor air emissions of NO₂, NH₃, CO and PM₁₀ from the stacks in MOPCO. The individual risk exposures from MOPCO have been evaluated and found to be below the maximum tolerable risk levels allowed by the Egyptian Environment Protection Low No. 4/1994.