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240692

ROLE OF CARDIAC MAGNATIC RESONANCE TISSUE MAPPING IMAGING IN ISCHEMIC HEART DISEASE

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

Medicine

Abstract

Background: The magnetic resonance imaging of the heart provides the distinctive opportunity to non-invasively evaluating the myocardium, and has become the gold standard for the assessment of viability. Objective: To examine the clinical application of cardiac magnetic resonance imaging (CMRI) native and post-contrast T1 map, as extensively as the T2 map, in ischemic heart disease in the form of diagnosis of myocardial edema and necrosis in cases of  acute myocardial infarction post percutaneous coronary intervention (PCI), and to evaluate their prognostic value. Patients and methods: A total number of 80 patients were scheduled for elective CMRI between December 2019 and April 2021. Our patients came to Al-Hussein Hospital, Cardiology Department with a clinical picture of an acute myocardial infarction subjected for PCI. They were referred to the CMRI unit at Al-Hussein Hospital one to two days post PCI for CMRI as a part of a research project. Follow up magnetic resonance imaging (MRI) was performed three to four months later. Results: This study involved 59 males and 21 females with a mean age of 53 (± 12) years. In our study, different tissue mapping values showed marked statistically difference between hyper enhanced (HE) and remote segments with P value <0.001. We detected microvascular obstruction in 50 patients (62.5%). In patients with microvascular obstruction (MVO), there was a difference (yet non statistically significant) in tissue mapping values between segments of MVO and hyper enhanced segments, with no MVO with tendency towards pseudo normalization of tissue mapping values of the MVO segments. The suggested cut off value of T2 map was 53.2ms with 80% sensitivity, 71% specificity, 74% positive predictive value, 78% negative predictive value, and 76% accuracy. There were two suggested cut off value of native T1 map: 1.    The first one was 1076.9 ms with 68% sensitivity, 80% specificity, 77% positive predictive value, 71% negative predictive value, and 74% accuracy. 2.    The second one was 1069 ms with 75% sensitivity, 73% specificity, 73% positive predictive value, 74% negative predictive value, and 74% accuracy. The suggested cut off value of the extra cellular volume (ECV) showed 78% sensitivity, 89% specificity, 88% positive predictive value, 80% negative predictive value, and 84% accuracy. Conclusion: The area at risk in cases of an acute coronary syndrome and suggested cut off values were with reasonable sensitivity, specificity and accuracy.

DOI

10.21608/amj.2022.240692

Keywords

Cardiac magnetic resonance tissue mapping

Authors

First Name

Mohammed

Last Name

Salah El-Feshawy

MiddleName

-

Affiliation

Departments of Diagnostic & Interventional Radiology, Faculty of Medicine, Al-Azhar University

Email

mohamedelfeshawy@azhar.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Ismail Abdo

MiddleName

-

Affiliation

Departments of Diagnostic & Interventional Radiology, Faculty of Medicine, Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Mostafa

Last Name

Fadel Sonbol

MiddleName

-

Affiliation

Departments of Diagnostic & Interventional Radiology, Faculty of Medicine, Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Mohammed

Last Name

Abou-Mandour Mousa

MiddleName

-

Affiliation

Departments of cardiology, Faculty of Medicine, Al-Azhar University

Email

-

City

-

Orcid

-

Volume

51

Article Issue

3

Related Issue

34623

Issue Date

2022-07-01

Receive Date

2022-05-31

Publish Date

2022-07-01

Page Start

1,603

Page End

1,618

Print ISSN

1110-0400

Link

https://amj.journals.ekb.eg/article_240692.html

Detail API

https://amj.journals.ekb.eg/service?article_code=240692

Order

23

Type

Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

Publication Link

https://amj.journals.ekb.eg/

MainTitle

ROLE OF CARDIAC MAGNATIC RESONANCE TISSUE MAPPING IMAGING IN ISCHEMIC HEART DISEASE

Details

Type

Article

Created At

22 Jan 2023