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10.21608/amj.2022.230453

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Background: The most common site of ectopic pregnancy is the fallopian tube. Most cases of tubal ectopic pregnancy that are detected early can be treated successfully either with minimally invasive surgery or with medical management using methotrexat, and did not have heterotopic pregnancy. Twenty five of patients were treated with letrozole (2.5 mg bid) for 10 days, and the other 25 patients were treated with methotrexate (1mg\kg IM, maximum 50mg single dose), and follow up by β-hCG on day 4 and day 7 of first dose at Obstetrics and Gynecology Department, Faculty of Medicine, Al-Azhar University Hospitals from April 2020 to March 2021. Results: The mean age of group 1 was 28.36 (±3.33 SD) with range (22-36) while the mean age of group 2 was 30.28 (±4.34 SD) with range (22-35). According to residence in group 1 there wer, and 15 (60%) urban resident, while in group 2 there were 11 (44%) rural resident and 14 (56%) urban resident. There was no statistically significant difference between the studied groups as regard age or residence. There was no statistically significant difference between the st, parity, and history of assisted reproductive. Presented by vaginal bleeding or presented by abdominal pain. There was significant difference between the different studied periods in group 1 as regard abdominal US, and significant difference between the different studied periods in group 2 as regard abdominal US. Conclusion: Letrozole was as effective as methotrexate, with success rates of 86% for both treatment arms. b-Human chorionic gonadotropin levels even appeared to decrease more rapidly for women treated with letrozole than methotrexate, although the difference was statistically significant

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51

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2

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32983

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1110-0400

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https://amj.journals.ekb.eg/article_230453.html

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Al-Azhar Medical Journal

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https://amj.journals.ekb.eg/