Background: Vitamin D deficiency has been associated with inflammation and endothelial and platelet dysfunction, which favours the risk of cardiovascular complications.
Objective: To study the correlation between serum vitamins 25(OH)-VD level and cardiac dysfunction in end stage renal disease patients on regular hemodialysis.
Patients and Methods: This was a cross-sectional study which done in Mustafa Kamel Military hospital an on 50 hemodialysis patients on regular hemodialysis for > 6 months to assess the correlation between serum vitamin D level and cardiac dysfunction in end stage renal disease patients on hemodialysis.
Results: In our patients, we discovered that there was a highly significant relation between vit D deficiency and cardiac dysfunction in HD patients we found strong relation between Vitamin D deficiency with coronary heart disease, decrease Ejection fraction (EF%), increase Left ventricular mass index (LVMI), End diastolic and End systolic and,Diastolic dysfunction and valvular calcification in HD patients with 25-hydroxyvitamin D insufficiency and deficiency.
Conclusion: Clinical studies among patients with CKD on HD have largely that a poor vitamin D status is an independent risk factor for prevalent and incident heart disease, including coronary vascular calcification, heart failure, and CV mortality.