Background: Gastritis is a very common prevalent pathological entities and endoscopists make judgements on the presence or absence of pangastritis on the basis of endoscopic appearances of the gastric mucosa. Objective: To analyze the correlation between the endoscopic findings and the histological diagnosis of pangastritis in early dyspeptic patients. Patients and methods: In this study was done on 180 patients complaining of newly onset dyspepsia coming to upper endoscopy unit at Al-Hussein University Hospital during from February 2019 until August 2019, after getting informed consent, detailed history was taken from patient that included dietetic, social, medical and family history of malignant diseases. Blood investigation was done, liver function test, kidney function test and complete blood count. Also abdominal ultrasonography was done in fasting patients. Results: By endoscopy we found that 67.8% of patients have pangastritis and by histopathology found that 88.9 % from patients have pangastritis. 66.7 % from studied patients have pangastritis by both endoscopy and histopathology. So, sensitivity of endoscope about 81.8 %, and PPV about 86.9 % and NPV of endoscopy in about 33.3 %. Conclusion: Pangastritis was a common finding in early dyspeptic patients and endoscopy has high sensitivity in diagnosis of pangastritis and normal endoscopic appearance did not rule it out and the histopathology was still the gold standard method for diagnosis.