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178685

CLINICOPATHOLOGIC STUDY OF BASAL CELL CARCINOMA: A SINGLE-CENTRE RETROSPECTIVE STUDY

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Medicine

Abstract

Background: Basal cell carcinoma (BCC) is the most common malignant neoplasm in fair-skinned individuals and accounts for about two-thirds of all skin cancers in Caucasians. BCC rarely metastasizes or causes death, but it can result in extensive morbidity through local invasion and tissue destruction. Objective: To evaluate the clinicopathologic features of basal cell carcinoma in Egyptian population. Patients and methods: Our study included 80 patients with BCCs from January 2015 to December 2019. A retrospective analysis of baseline clinical and histopathological data was for all subjects incorporated in the study. Data needed for the study were obtained from the case files. Patients were histologically diagnosed at Dermatopathology unit of Department of Dermatology and Venereology, Al-Hussein University Hospital, Cairo, Egypt. Results: The present study showed that the clinical  types of  BCC  of  the  involved patients were 41 lesions (39%) of ulcerative type, 39 lesions (37.1%) of nodular non pigmented type, 13 lesions (12.4%) of nodular pigmented type, 9 lesions (8.6%) of superficial type, and 3 lesions (2.9%) of advanced type. As regards the histological subtypes, 52 lesions (49.5%) were nodular, 11 lesions (15.9%) were pigmented, 9 lesions (8.6%) were adenoid, 9 lesions (8.6%) were superficial, 8 lesions (7.67%) were infiltrative, 7 lesions (6.7%) were micro-nodular, 6 lesions (5.7%) were nodulo-cystic and 3 lesions (4.3%) were baso-squamous. Conclusion: Based on our findings, BCC was strongly associated with exposure to ultraviolet (UV) radiations. Tumors developed mainly on the sun-exposed skin of elderly individuals. Nodular BCC was the most common clinical and histological subtype.

DOI

10.21608/amj.2021.178685

Keywords

Clinicopathologic Study, basal cell carcinoma, Retrospective study

Authors

First Name

Ahmed

Last Name

Mustafa Abd El-Wahab Al-Bayomi

MiddleName

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Affiliation

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University

Email

a7madsasa@gmail.com

City

-

Orcid

-

First Name

Hussein

Last Name

Mohamed Hassab El-Naby

MiddleName

-

Affiliation

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Mohammed

Last Name

Abd El-Mawgoud Amer

MiddleName

-

Affiliation

Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Al-Azhar University

Email

-

City

-

Orcid

-

Volume

50

Article Issue

3

Related Issue

25707

Issue Date

2021-07-01

Receive Date

2021-06-20

Publish Date

2021-07-01

Page Start

2,251

Page End

2,260

Print ISSN

1110-0400

Link

https://amj.journals.ekb.eg/article_178685.html

Detail API

https://amj.journals.ekb.eg/service?article_code=178685

Order

58

Type

Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

Publication Link

https://amj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023