Background: Periorbital hyperpigmentation, generally called dark circles, is a condition characterized by relatively dark coloration of the periorbital eyelids. It is a common worldwide problem which makes a person appear tired, sad, and aged. Although this condition does not cause physical morbidity, it can pose a substantial cosmetic problem and, eventually, affect the quality of the effected individual.
Objective: To evaluate the efficacy of platelet rich plasma versus autologous emulsified fat in the treatment of infraorbital dark circle.
Patients and methods: Our study was carried out on 30 patients presenting with infraorbital dark circles of different etiological factors divided into A and B from December 2019 to July 2020.All patients were recruited from the Dermatology outpatient clinic of Al-Azhar University Hospitals. Patients were divided into two equal groups: Group A treated with platelet rich plasma (PRP) and Group B treated by autologous fat injection.
Results: The present study showed excellent response of 3 patients (20%) in group A, and 7 patients (46.7%) in group B. Moderate response occurred in 2 patients (13.3%) in group A, and 4 patients (26.7%) in group B. Mild response occurred in 2 patients (13.3%) in group A, and 3 patients (20%) in group B. No response occurred in 8 patients (53.3%) in group A and 1 patient (6.7%) in group B.
Conclusion: Both PRP and emulsified fat were effective in treatment of infraorbital dark circles with statistically significant difference as regard the improvement, patient satisfaction and postoperative complications at the end of treatment period and follow up for six months.