Background: Preterm labor means delivery before thirty-seven completed weeks of gestational age of pregnancy. Premature rupture of membranes occurs in three percent of pregnancies and considered the main cause of one third of preterm deliveries.
Objective: To determine whether serum ferritin levels could be used as a predictive marker of premature rupture of membranes or not.
Patient and Methods: Descriptive prospective comparative study started from September 2019 till March 2020. This study was conducted on pregnant females (30-37 weeks). Serum ferritin was high among group I when compared with group II. One hundred healthy pregnant women were enrolled in this study and full field the following criteria from September 2019 till March 2020 at Al- Hussein University Hospital.
Results: The results were tabulated and statistically analyzed by suitable statistical methods after completion of the study. And it shows highly statistically significant increase in gestational age in intact membrane group compared to PROM group and statistically significant increase in serum ferretin in PROM group compared ti intact membrane group. Also there was an inverse correlation between serum ferretin and gestational age while there is a direct correlation between serum ferretin and hematocrit value. There is a non-significant difference between both groups according to maternal age, hemoglobin or hematocrit.
Conclusion: Serum ferritin is a marker for preterm premature rupture of membranes, and could be used to expect complications by obstetricians, and it considered more specific for prediction.