Background: Abortion is the interruption and/or termination of pregnancy, either spontaneously or intentionally, before the fetus develops sufficiently to survive. About 80% of abortions occur in the first 12 weeks of pregnancy. The underlying mechanism in about half of cases involves chromosomal abnormalities.
Objective: To evaluate the association between TSH, T3, T4, anti-thyroglobulin antibody and thyroid peroxidase antibody in women with spontaneous abortion.
Patients and methods: This study was conducted on 60 female patients in the age group of 21–35 years recruited from the outpatient and inpatient clinics of the Department of Obstetrics and Gynecology, Tanta University Hospital, this study period February 2019 to July 2020. Approval of the medical ethics committee and signing written informed consent. The levels of TSH, T3, T4, antithyroglobin antibody and thyroid peroxidase antibody were determined.
Results: There was no statistically significant relation between spontaneous abortion and TSH, T3, T4, anti-thyroglobulin antibody and thyroid peroxidase antibody.
Conclusion: No need to screen for subclinical hypothyroidism and thyroid autoimmunity in all pregnancy.