Background: Endometrial cancer (EC) is the most common malignancy of the female reproductive tract. Most patients are diagnosed with an early-stage disease, and the overall survival for stage I in about 85–91%.
Objective: To assess the role of pelvic lymphadenectomy in management of early stage endometrial carcinoma in order to determine whether the patient is in need to postoperative radiotherapy or not.
Patients and Methods: This was a prospective observational study included 52 postmenopausal patient who complained from vaginal bleeding and underwent endometrial biopsy revealing the presence of endometrial hyperplasia with atypia or grade 1 endometrial adenocarcinoma attended the Gynecological clinic at Maadi Military Hospital Cairo, Egypt from March 2018 to February 2020.
Results: Myometrial invasion in MRI ‌‌and histopathology was 73.1% and 65.4% respectively, with no statistically significant difference. Parametrial invasion was 7.7% and 9.6% respectively with no statistically significant difference. Regarding to pelvic nodal invasion in MRI and histopathology, it was 15.4% and 38.5% respectively with a statistically significant difference.
Conclusion: Pelvic lymphadenectomy demonstrated clinical benefit in patients with early stage endometrial cancer and could be a standard treatment option.