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82567

ASSOCIATION BETWEEN NEUTROPHIL TO LYMPHOCYTE RATIO AND INFLAMMATORY MARKERS IN HEMODIALYSIS PATIENTS

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Last updated: 22 Jan 2023

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Abstract

Back ground: Hemodialysis patients have an inflammatory state which is attributed to their morbidity and mortality compared to the general population. Objective: To study the association between neutrophil to lymphocyte ratio and other inflammatory markers: (Interleukin-6 (IL-6), high sensitive C reactive protein (hs-CRP), and other inflammatory markers) in hemodialysis patients. Patients and methods: Forty two hemodialysis patients. Participated in this study. They divided into two groups. Group I: Patients whose hs-CRP > 10 mg. Group II: Patients whose hs-CRP < 10 mg. The association between neutrophil to lymphocyte ration and the other inflammatory markers war studied. Results: 69% of the patients (29 patient) whose hs-CRP were more than 10 mg and 31% of the patients (13 patients) whose hs-CRP were less than 10 mg. Additionally, there has been a positive correlation between neutrophil to lymphocyte ratio and interleukin-6 along with platelet to lymphocyte ratio. Moreover, interleukin 6 that indicated inflammation in hemodialysis, was more than 30 ng. Further, the value of neutrophil to lymphocyte ratio which represented the inflammation in hemodialysis patients, was equal or more than 1.6. Conclusion: Cardiovascular condition of hemodialysis patients affects their morbidity and mortality. Consequently, it could be assessed by neutrophil to lymphocyte ratio which has high specificity and sensitivity.

DOI

10.21608/amj.2020.82567

Keywords

CRP, WBCs, ESR, ulcerative colitis

Authors

First Name

Hafez

Last Name

Ahmed Abd El-Hafeez

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Affiliation

Departments of Internal Medicine,Faculty of Medicine, Al-Azhar University-Cairo, Egypt

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First Name

Ahmed

Last Name

Mohammed Al-Ashkar

MiddleName

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Affiliation

Departments of Internal Medicine,Faculty of Medicine, Al-Azhar University-Cairo, Egypt

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Orcid

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First Name

Nagah

Last Name

Mohamed Abo Mohamed

MiddleName

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Affiliation

Departments of Clinical Pathology, Faculty of Medicine, Al-Azhar University-Cairo, Egypt

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Orcid

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First Name

Mohammed

Last Name

Ibrahim Khalil

MiddleName

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Affiliation

Departments of Internal Medicine, Faculty of Medicine, Al-Azhar University-Cairo, Egypt

Email

dr_zohair@yahoo.com

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Orcid

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Volume

49

Article Issue

2

Related Issue

10133

Issue Date

2020-04-01

Receive Date

2020-04-15

Publish Date

2020-04-01

Page Start

491

Page End

502

Print ISSN

1110-0400

Link

https://amj.journals.ekb.eg/article_82567.html

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https://amj.journals.ekb.eg/service?article_code=82567

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14

Type

Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

Publication Link

https://amj.journals.ekb.eg/

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Article

Created At

22 Jan 2023