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61447

EFFECT OF MUSIC AND NOISE ON GROWTH AND MATURATION IN FEMALE ALBINO RAT

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Last updated: 22 Jan 2023

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Abstract

Background:Noise stress is implicated in various illnesses of human, and it is responsible for increased morbidity associated with modern life style. Music induces emotions which are often accompanied by physiological reactions. Objective:Investigating the effect of light music and noise on growth and maturation from weaning to puberty in female rat with studying the histological structuresof pituitary, thyroid and ovaries. Material and Methods:Fifty animals were used in this work and divided into five equal groups: ● Control group. ● Rats exposed to noise for 60 days (over 90db, 1h/day). ● Rats exposed to music for 60 days (1h/day). ● Rats exposed to music then noise for 60days (2h/ day). ● Rats exposed to noise then music for 60days (2h/ day).      At the end of experiment, serum was obtained from the rats during the di-estrous phase for determination of: 1. Growth hormone. 2. TSH level. 3. Gonadotrophic hormones (FSH, LH). 4. Prolactin hormone. 5. Leptin hormone.      Histopathological study for pituitary, thyroid and ovaries were done. Results: This study revealed that noise caused significant decrease in gonadotrophic hormones (LH, FSH) and TSH, with significant increase in serum leptin without any changes in both growth and prolactin hormones. In addition, it produced significant pathological changes in pituitary, thyroid, ovaries and uterus. These changes included congested dilated blood sinusoids and loss of normal cellular arrangement. On the other hand, music caused insignificant changes in gonadotrophic hormones (LH, FSH) and TSH levels, with significant increase in leptin hormone without any changes in both growth and prolactin hormones levels. In addition, it produced insignificant pathological changes in pituitary, thyroid and ovaries as compared with the control group. Conclusions: Exposure to noise stress could affect the process of reproduction but does not affect the process of growth. In addition, listening to light music does not disturb the process of reproduction or growth. Where there was an equilibrium in biochemical and histological results.

DOI

10.12816/0034737

Authors

First Name

Mohamed

Last Name

Zakarya El-Etreby

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Affiliation

Medical Physiology, Department, Al-Azhar Faculty of Medicine

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First Name

Hussein

Last Name

Mohamed El Sayed

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Affiliation

Medical Physiology, Department, Al-Azhar Faculty of Medicine

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First Name

Ezz- Eldin

Last Name

Elsharkawy Abdulla

MiddleName

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Affiliation

Histology Departments, Al-Azhar Faculty of Medicine

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First Name

Amer

Last Name

Mohamed Abd-Elhameed

MiddleName

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Affiliation

Biochemistry Departments, Al-Azhar Faculty of Medicine

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First Name

Walid

Last Name

Mustaf Said Ahmed

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Affiliation

Medical Physiology Departments, Al-Azhar Faculty of Medicine

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Volume

45

Article Issue

4

Related Issue

8928

Issue Date

2016-10-01

Receive Date

2016-10-01

Publish Date

2016-10-01

Page Start

717

Page End

734

Print ISSN

1110-0400

Link

https://amj.journals.ekb.eg/article_61447.html

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https://amj.journals.ekb.eg/service?article_code=61447

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6

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Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

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https://amj.journals.ekb.eg/

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Article

Created At

22 Jan 2023