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59738

DYNAMIC AND DIFFUSION MAGNETIC RESONANCE IMAGING IN EVALUATION OF MALIGNANT HEPATIC NEOPLASMS AFTER PERCUTANEOUS RADIOFREQUENCY ABLATION

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Last updated: 22 Jan 2023

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Abstract

Background: Evaluation of hepatic malignancies response after loco-regional treatment is crucial to assess treatment success and to guide future therapy. MRI DWI liver added to conventional unenhanced and contrast enhanced MRI always be used in the follow up of RFA showing promising results in the detection of ablation site recurrence/residual lesions. Objective: Evaluation of the role of dynamic and diffusion MRI in evaluation of recurrent/residual hepatic neoplasms after radiofrequency ablation. Patients and methods: This prospective study included 50 patients, 40 males and 10 females. Patients ages ranged between 45 and 80 years with the mean age of 57.02 years, (SD±8.07). Patients were referred from Tropical Medicine Department to MRI unit after the procedure of radiofrequency ablation of complete ablated malignant liver tumors. Results: Thirty seven patients (74%) had resolved lesions, while 13 patients (26%) had recurrent/residual lesions. The border of resolved lesions were smooth, but in unresolved lesions were nodular in 11 patient out of 13 (84.6%), and irregular in two patients (15.4%). The measured cut off value between the completely ablated lesions and residual/recurrent lesions was 1.05x10-3 mm2/s. The ablation zones can be differentiated from liver parenchyma visually in the DWIs and by means of ADC in all patients. There were no statistical differences in the mean ADC values between the ablation zones of the resolved and unresolved lesions. Conclusion: Dynamic and DWI showed viable tumor regions, and suspected areas in the periphery of the ablation zone could be identified more easily, and analyzed precisely in conjunction with the conventional T1 and T2 WIs.

DOI

10.12816/0029140

Keywords

Diffusion weighted Image (DWI), Apparent Diffusion Coefficient (ADC) and Radiofrequency ablation (RFA)

Authors

First Name

Mohammad

Last Name

Mostafa

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Affiliation

Departments of Radiodiagnosis, Faculty of Medicine, Al-Azhar University, New Damietta and Girl Faculty in Cairo

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First Name

Abdullah

Last Name

Hussein

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Affiliation

Departments of Radiodiagnosis, Faculty of Medicine, Al-Azhar University, New Damietta and Girl Faculty in Cairo

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City

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Orcid

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First Name

Farid

Last Name

Atia

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Affiliation

Departments of Tropical Medicine, Al-Azhar New Damietta- Egypt

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Volume

45

Article Issue

2

Related Issue

8926

Issue Date

2016-04-01

Receive Date

2016-04-01

Publish Date

2016-04-01

Page Start

417

Page End

434

Print ISSN

1110-0400

Link

https://amj.journals.ekb.eg/article_59738.html

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https://amj.journals.ekb.eg/service?article_code=59738

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19

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Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

Publication Link

https://amj.journals.ekb.eg/

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Article

Created At

22 Jan 2023