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56795

CHROMOSOMAL ABNORMALITIES IN SEVERE OLIGOZOOSPERMIC INFERTILE MALES

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Last updated: 04 Jan 2025

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Abstract

Background: Genetic abnormalities account for 15-30% of infertility in males.Chromosomal abnormalities alone are responsible for approximately 5% of male infertility.
Objective: Determining the prevalence and type of chromosomal abnormalities in a group of infertile Egyptian males with severe oligozoospermia.
Patients and methods: Karyotyping was performed on peripheral blood lymphocyte samples of 60 infertile Egyptian men with severe oligozoospermia (sperm count ≤ 5×106/ml)during the period between April 2015 and June 2016.
Results: Out of the 60 patients studied, chromosomal abnormalities were identified in 5 (8.33%) patients. All the identified abnormalities were structural autosomal abnormalities.
Conclusion: These results highlighted the importance of genetic screening and counselling for males with severe oligozoospermia before scheduling them for any of the assisted reproduction techniques.

DOI

10.12816/0040348

Authors

First Name

Ali

Last Name

Ramadan Rabie

MiddleName

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Affiliation

Department of Dermatology, Venereology and Andrology, Al-Azhar University Faculty of Medicine

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Orcid

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First Name

Ahmad

Last Name

Kamel Seddeik Abdel-Hameed

MiddleName

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Affiliation

Department of Dermatology, Venereology and Andrology, Al-Azhar University Faculty of Medicine Assisted reproduction unit, the International Islamic Centre for Population Studies and Research (IICPSR), Al-Azhar University

Email

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City

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Orcid

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First Name

Mahmoud

Last Name

Fawzy Abdel Hamid

MiddleName

-

Affiliation

Department of Dermatology, Venereology,

Email

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City

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Orcid

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First Name

Hesham

Last Name

Fayek Ismail Kayed

MiddleName

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Affiliation

Department of Human Cytogenetics, National Research Centre

Email

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City

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Orcid

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First Name

Ahmed

Last Name

Mohamed Maher Abdel Rahman

MiddleName

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Affiliation

Misr University for Science and Technology

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Volume

46

Article Issue

3

Related Issue

8502

Issue Date

2017-07-01

Receive Date

2017-07-01

Publish Date

2017-07-01

Page Start

595

Page End

606

Print ISSN

1110-0400

Article File

AMJ_Volume 46_Issue 3_Pages 595-606.pdf

PDF . 740.2kB

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https://amj.journals.ekb.eg/article_56795.html

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https://amj.journals.ekb.eg/service?article_code=56795

Order

4

Type

Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

Publication Link

https://amj.journals.ekb.eg/

MainTitle

CHROMOSOMAL ABNORMALITIES IN SEVERE OLIGOZOOSPERMIC INFERTILE MALES

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Article

Created At

22 Jan 2023