54635

HUMAN CHORIONIC GONADOTROPHIN FOLLOWING ORCHIDOPEXY FOR UNILATERAL PALPABLE UNDESCENDED TESTIS: EFFECT ON TESTICULAR VOLUME AND VASCULARITY

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Last updated: 04 Jan 2025

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Abstract

Background: Cryptorchidism is a common male genital anomaly discovered at birth. Orchiopexy is the sole curative option. However, hormonal treatment has its potential role.  The type and regimen of hormonal treatment is widely different. 
Objective:  To evaluate the effect of the use of human chorionic gonadotrophin (hCG) as an adjunctive therapy after orchiopexy.
Patients and Methods: The study included 60 boys presented with unilateral palpable undescended testis. Their ages at presentation ranged between 10 months and 6 years.  All patients were subjected to history taking, clinical and radiological examination and orchiopexy. Patients were randomized into two equal groups. Randomization was done by a closed envelope that opened 2 weeks postoperatively by a nurse not included in the study. Group A received supportive hCG injection, two weeks after operation by single intramuscular injection weekly for 4 consecutive weeks. The dose was adjusted according to patient weight (< 10kg received 500 IU/week; 10-20 kg received 1000 IU/week and above 20 kg received 1500 IU/week).  Group B received orchiopexy without postoperative hormonal support. 
Results:  About 88.4% of studied children were underwent orchiopexy in the first two years of life. Both groups were comparable as regard to pre-intervention hormonal profile, and testicular volume before intervention, while after the intervention, volume significantly increased in group A with good blood supply.
Conclusion:  hCG postoperative supplementation for children with unilateral palpable undescended testis appears to be beneficial in subsequent outcome as expressed by increase in the size and vascularity of the testis.

DOI

10.21608/0047702

Keywords

Undescended testis, Orchidopexy, Human chorionic gonadotrophin, Testicular volume

Authors

First Name

Ibrahim

Last Name

Mahmoud Elsayaad

MiddleName

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Affiliation

Pediatric Surgery Departments; Faculty of Medicine (Damietta)

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Orcid

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First Name

Ahmed

Last Name

Fekry El-Deek

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Affiliation

Radiodiagnostics Departments; Faculty of Medicine (Damietta)

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Orcid

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Volume

47

Article Issue

1

Related Issue

8010

Issue Date

2018-01-01

Receive Date

2018-01-01

Publish Date

2018-01-01

Page Start

129

Page End

138

Print ISSN

1110-0400

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https://amj.journals.ekb.eg/article_54635.html

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https://amj.journals.ekb.eg/service?article_code=54635

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11

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Original Article

Type Code

941

Publication Type

Journal

Publication Title

Al-Azhar Medical Journal

Publication Link

https://amj.journals.ekb.eg/

MainTitle

HUMAN CHORIONIC GONADOTROPHIN FOLLOWING ORCHIDOPEXY FOR UNILATERAL PALPABLE UNDESCENDED TESTIS: EFFECT ON TESTICULAR VOLUME AND VASCULARITY

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Article

Created At

22 Jan 2023