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Clinical Research (Surgical)
Abstract
Background: Malignant pleural mesothelioma (MPM) is a rare and aggressive malignancy arising from the mesothelial cells lining the pleural cavity. Treatment options include surgery, chemotherapy, radiation, and multimodality treatment. Objective: This study is designed to identify the short terms benefits and risks of surgical options for patients of mesothelioma with pleural effusion. Patients and Methods: This study was held at Suez Canal university hospitals and designed as a randomized control clinical trial all patients with proven diagnosis of mesothelioma with pleural effusion were included and randomized over 3 groups; Group A: patients underwent evacuation with a chest tube and pleurodesis by talc powder slurry. Group B: patients underwent VATs evacuation and pleurodesis. Group C: patient undergone VATs partial pleurectomy with decortication. Results: The patients were predominantly males; the pain scale was from 4 to 8 on a visual analogue scale with a mean of 6.315 patients (42.9%) undergone evacuation with a chest tube and pleurodesis while 10 patients (28.6%) underwent VATS pleurodesis with talc poudrage also 10 patients (28.6%) undergone VATs partial pleurectomy from which 6 (17.1%) patients required decortication for trapped lung. with mean 7 days and the post-operative pain ranged on VAS scale from 2 to 9 with a mean of 4 while postoperative air leak occurred in 5 patients (14.3%) and postoperative wound infection in a total of 13.4 %. Conclusion: VATs partial pleurectomy seems to be a good method in the management of mesothelioma as it operatively allows the benefit of managing lung entrapment and allows better lung expansion and is postoperatively associated with superior control on effusion recurrence.
DOI
10.21608/scumj.2022.272128
Keywords
mesothelioma, VATS, Pleurectomy, Pleurodesis
Authors
Affiliation
Department of Cardiothoracic Surgery, Faculty of Medicine, Suez Canal University, Egypt
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Department of Cardiothoracic Surgery, Faculty of Medicine, Suez Canal University, Egypt
Email
hanydomiaty@gmail.com
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Department of Cardiothoracic Surgery, Faculty of Medicine, Suez Canal University, Egypt
Email
ramysamircts@gmail.com
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https://scumj.journals.ekb.eg/article_272128.html
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https://scumj.journals.ekb.eg/service?article_code=272128
Publication Title
Suez Canal University Medical Journal
Publication Link
https://scumj.journals.ekb.eg/
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