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262059

Renal Failure Index and Assessment of Kidney Function in Preterm versus Full Term Neonates

Article

Last updated: 04 Jan 2025

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Clinical Research (Medical)

Abstract

Background:Prematurity is associated with one-third of all infant deaths. In recent years, there was increasing evidence to indicate that prematurity is an independent risk factor for chronic kidney diseases. Diagnosis of acute renal failure is difficult in neonates as many of the established clinical and biochemical parameters are unreliable in this age group. However, fractional excretion of sodium and the renal failure index was found to be the most useful in evaluating babies with renal failure. Aim:reduction of morbidities and mortalities resulting from neonatal acute renal failure. Objectives:Early detection and proper management of neonates at risk of developing renal injury either prerenal or intrinsic renal failure will protect them against injury risk. Subjects and Methods: This is a cross-sectional study, performed in the neonatal intensive care unit of Suez Canal University hospital on 80 neonates during the period from January 2019 to January 2020. Complete blood picture, C-reactive protein, serum sodium and creatinine, and urine sodium and creatinine were investigated. Results:There was significant difference between preterm and full-term neonates in hemoglobin (14.88±3.3 vs. 16.37±2.7 g/dl), platelets (204.42 vs. 249.5*103/mm3), serum creatinine (0.74 vs. 0.46 mg/dl), and serum sodium (140 vs. 138 meq/l), urinary creatinine (25 vs. 30mg/dl),Fraction excretion of sodium (FENa) (1.09 vs. 0.51) and Renal failure index (RFI) (1.6 vs. 0.69). Conclusions:Prematurity itself is a risk factor for developing kidney injury, it is commonly associated with high morbidity and mortality. The results of this study demonstrate that preterm neonates had renal failure index and fractional excretion of sodium higher than full-term neonates.
 

DOI

10.21608/scumj.2022.262059

Keywords

acute renal failure, prematurity, Assessment

Authors

First Name

Amany

Last Name

Shehab

MiddleName

W.

Affiliation

Department of Pediatrics, Damietta Specialized Hospital

Email

amanyshehab2020@yahoo.com

City

-

Orcid

-

First Name

Nouran

Last Name

Abdullah

MiddleName

B.

Affiliation

Department of Pediatrics, Faculty of Medicine, Suez Canal University, Egypt

Email

nouranboym2@hotmail.com

City

-

Orcid

-

First Name

Naglaa

Last Name

Salem

MiddleName

E.

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Egypt

Email

naglaelwy76@gmail.com

City

-

Orcid

-

First Name

Enas

Last Name

Elnagar

MiddleName

F.

Affiliation

Department of Pediatrics, Faculty of Medicine, Suez Canal University, Egypt

Email

dr-enas.elnagar@yahoo.com

City

-

Orcid

-

Volume

25

Article Issue

3

Related Issue

36846

Issue Date

2022-10-01

Receive Date

2022-09-29

Publish Date

2022-10-01

Print ISSN

1110-6999

Online ISSN

2090-2581

Link

https://scumj.journals.ekb.eg/article_262059.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=262059

Order

5

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Renal Failure Index and Assessment of Kidney Function in Preterm versus Full Term Neonates

Details

Type

Article

Created At

22 Jan 2023