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207565

Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria

Article

Last updated: 04 Jan 2025

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Tags

Clinical Research (Medical)

Abstract

Background: Hepatitis C virus (HCV) infection is a worldwide public health problem, affecting about 3% of the world's population. The introduction of sofosbuvir (Sovaldi) markedly changed therapeutic outcomes. The assessment of HRQoL in HCV patients under treatment might help to better understand the effect of treatment on the patient's quality of life. Aim: The study was conducted to assess the quality of life of chronic hepatitis C patients receiving Sovaldi at the outpatient hepatology clinic in Sharq Almadina hospital. Patients and Methods: A cross-sectional survey was conducted among chronic hepatitis C patients receiving Sovaldi treatment regimen for at least 3 months. Data was collected from the studied CHCV patients using face-to-face interviews including personal & sociodemographic characteristics, The chronic liver disease questionnaire (CLDQ) to assess health-related quality of life, and the translated Arabic version of the short-form (SF 36) generic quality of life questionnaire. In addition, reviewing the medical records of studied CHCV patients to collect data about their laboratory findings was done. Results:More than two-thirds of studied patients (69.1%) discovered the disease during the National Egyptian Campaign. The overall median value of SF-36Q items was 53.19 indicating a poor HRQoL. There were significant positive correlations between the majority of SF-36Q individual domain scores and that for CLDQ P Conclusions: There were significant positive correlations between the majority of SF-36Q individual domain scores and that for CLDQ as well as the total scores.

DOI

10.21608/scumj.2022.207565

Keywords

HCV, Sovaldi, QOL

Authors

First Name

Nahla

Last Name

Gamaleldin

MiddleName

-

Affiliation

Department of Community Medicine, Faculty of Medicine, University of Alexandria, Egypt

Email

nahla.gamal@alexmed.edu.eg

City

-

Orcid

0000-0002-1083-9120

First Name

Nagwa

Last Name

Shokeir

MiddleName

-

Affiliation

Department of Community Medicine, Faculty of Medicine, University of Alexandria, Egypt

Email

ngshokair@yahoo.com

City

-

Orcid

-

First Name

Hend

Last Name

Abdelaziz

MiddleName

H

Affiliation

Department of Family Medicine, Ministry of Health, Egypt

Email

dody_zuma_2008@yahoo.com

City

-

Orcid

-

First Name

Heba

Last Name

Elweshahy

MiddleName

-

Affiliation

Department of Community Medicine, Faculty of Medicine, University of Alexandria, Egypt

Email

elweshahi2006@yahoo.com

City

-

Orcid

-

Volume

25

Article Issue

1

Related Issue

28782

Issue Date

2022-03-01

Receive Date

2021-12-03

Publish Date

2022-03-01

Page Start

42

Page End

56

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 25_Issue 1_Pages 42-56.pdf

PDF . 426.7kB

Link

https://scumj.journals.ekb.eg/article_207565.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=207565

Order

5

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Quality of Life of Chronic Hepatitis C Patients Receiving Sovaldi Treatment Regimen at Sharq Almadina Hospital in Alexandria

Details

Type

Article

Created At

22 Jan 2023