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204007

Acute Meningitis in Mansoura Fever Hospital

Article

Last updated: 22 Jan 2023

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Clinical Research (Medical)

Abstract

Background: Meningitis is a serious health problem that results in grave morbidity and mortality. It is caused by several organisms and present with various presenting pictures imparting some challenge. Aim: Highlighting the etiology and prognosis of acute meningitis in Mansoura Fever Hospital. Subjects and Methods: A prospective cross sectional observational study. The study included 350 cases admitted with suspected meningitis. Lumbar puncture: for collection of cerebrospinal fluid (CSF) samples. CSF analysis, microbiological examination of CSF, and blood culture and antibiotic sensitivity test were done. Brain magnetic resonant imaging (MRI) was performed before lumbar puncture in some patients. Detailed analysis of epidemiologic characteristics, clinical data and laboratory findings, the causative organisms, prognosis of all the patients with acute bacterial meningitis (ABM) were studied. Results: Meningitis occurred at all age groups. A significant proportion of meningitis patients (60%) reported a positive history of antibiotic intake in the few days (3-5) before admission to the hospital. 79.1% of ABM patients had a CSF leukocyte count in the range of > 100 up to 1,000 cell/mm3 and 80% had CSF neutrophil percentage > 50%. The pathogens were detected by direct Gram-stained smear in 86.4% of patients. Gram +ve bacteria was detected in 55/110 (50%) of cases. Gram -ve bacteria detected in 40/110 (36.4%) of cases. ABM carried a high mortality rate (22.7%). ABM had 22.7% mortality rate. Conclusions: Meningitis is endemic in Egypt with a significant mortality rate. Strept pneumonia was the most common offending organism.
 

DOI

10.21608/scumj.2022.204007

Keywords

acute bacterial meningitis, CSF markers, Epidemiology, mortality

Authors

First Name

Sameh

Last Name

Abdel Monem

MiddleName

-

Affiliation

Department of Tropical Medicine, Faculty of Medicine, Zagazig University.

Email

drsameh154@gmail.com

City

-

Orcid

-

First Name

Aya

Last Name

Al Amely

MiddleName

-

Affiliation

Department of Tropical Medicine, Faculty of Medicine, Zagazig University.

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Sharaf

MiddleName

-

Affiliation

Department of Tropical Medicine, Faculty of Medicine, Zagazig University.

Email

-

City

-

Orcid

-

First Name

Naglaa

Last Name

Khalifa

MiddleName

A

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Zagazig University.

Email

-

City

-

Orcid

-

First Name

Omima

Last Name

Taha

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University.

Email

omimatharwat@yahoo.com

City

-

Orcid

-

Volume

25

Article Issue

1

Related Issue

28782

Issue Date

2022-03-01

Receive Date

2021-11-10

Publish Date

2022-03-01

Page Start

13

Page End

21

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 25_Issue 1_Pages 13-21.pdf

PDF . 398.6kB

Link

https://scumj.journals.ekb.eg/article_204007.html

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https://scumj.journals.ekb.eg/service?article_code=204007

Order

2

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023