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159779

Evaluation of the Outcome of the Use of 2% Lidocaine Irrigation in the Prevention of Abdominal Surgical Site Infection

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Clinical Research (Surgical)

Abstract

Background:Surgical site infection (SSI) is the third most common nosocomial infection, associ­ated with higher morbidity and mortality rates as well as increased cost and prolonged hospital stay for patients. Lidocaine, in addition to being a readily available and accessible local anesthetic, has shown antimicrobial and fungicidal activity. Objectives: Assessing the outcome of using 2% lidocaine irrigation in the prevention of abdominal SSI in grade II (clean-contaminated), Grade III (contaminated) wounds. Subjects and Methods: This prospective randomized clinical trial included patients who underwent elective and emergency abdominal surgeries in the Department of General Surgery at Suez Canal University Hospitals. The participants were randomly divided in two groups: A study group, who received sterile saline plus Lidocaine 2%. And a control group, who received sterile saline only to compare the 30-day postoperative infection outcomes among them. Results: 56.8% of participants were males. The mean age of participants was 48.88 ± 10.18 years. The study group patients had statistically significant lower incidents of SSI than the control group (p=0.03). The overall incidence of SSI was 38.6%. The most prevalent sign of the SSI was pus in 35.3% and in 76.5% of the patients' SSI lasted for two weeks. There was no statistically significant difference between both groups regarding their hospital stay duration, laboratory measures, and other postoperative complications. Conclusions: 2% lidocaine application before skin closure in grade II and grade III wounds decreased the incidence of SSI) in patients undergoing abdominal surgery.

DOI

10.21608/scumj.2021.159779

Keywords

Surgical site infection (SSI), Lidocaine, prevention

Authors

First Name

Ahmed

Last Name

Ghanem

MiddleName

M

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University Hospitals and Medical School, Ismailia, Egypt

Email

ahmedghanem215@gmail.com

City

-

Orcid

-

First Name

Mustafa

Last Name

Abou-Ali

MiddleName

-

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University Hospitals and Medical School, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Hussein

MiddleName

H

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University Hospitals and Medical School, Ismailia, Egypt

Email

ahmedhassan@med.suez.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Anwar

MiddleName

M

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University Hospitals and Medical School, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Sameh

Last Name

Abu-Elela

MiddleName

T

Affiliation

Department of Surgery, Faculty of Medicine, Suez Canal University Hospitals and Medical School, Ismailia, Egypt

Email

-

City

-

Orcid

-

Volume

24

Article Issue

1

Related Issue

22901

Issue Date

2021-03-01

Receive Date

2021-03-29

Publish Date

2021-03-01

Page Start

29

Page End

40

Print ISSN

1110-6999

Online ISSN

2090-2581

Link

https://scumj.journals.ekb.eg/article_159779.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=159779

Order

4

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Evaluation of the Outcome of the Use of 2% Lidocaine Irrigation in the Prevention of Abdominal Surgical Site Infection

Details

Type

Article

Created At

22 Jan 2023