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119622

Colonoscopic and Histopathological Findings in Patients with Various Lower Gastrointestinal Symptoms: A Single-Center Experience

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Last updated: 22 Jan 2023

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Abstract

Background: Early diagnosis of lower gastrointestinal (GI) diseases constitutes a challenge. While colonoscopy helps in the detection of these diseases; histopathological analysis of obtained biopsies is of greater importance. Aim: This study aimed at the identification of colonic lesions associated with common lower GI manifestations based on colonoscopy and histopathological examination of biopsies. Materials and Methods: In a retrospective cross-sectional study, we included medical records of 710 patients involving their personal, clinical, endoscopic, and pathological data. Included data were of patients who presented with lower GI manifestations, and underwent colonoscopy and biopsy taking in the period from January 2016 to June 2020. Results: The most found pathology was non-specific chronic colitis (NSCC) (59.7%), followed by malignancy 19.3%) then inflammatory bowel disease (IBD) (15.6%), hyperplastic inflammatory polyp in 3.7%. Meanwhile, bilharzial colitis was diagnosed in 1.3% of patients. Significant predictors of both NSCC and malignancy were advanced age (<0.001), diabetes, hypertension, abdominal pain, diarrhea, and bloody diarrhea. In addition, bleeding per rectum and weight loss were also found to be specific predictors in malignancy. The only predictors of IBD were abdominal pain and bloody diarrhea and weight loss. Conclusions: NSCC, malignancy, and IBD are the most common causes of lower GI manifestations. Moreover, clinical predictors of these diseases are useful in the early diagnosis and management of colonic lesions.
 

DOI

10.21608/scumj.2020.119622

Keywords

colonoscopy, colorectal cancer, IBD, colitis, diarrhea, Bleeding per rectum

Authors

First Name

Fatma

Last Name

Moussa

MiddleName

-

Affiliation

Department of Infectious, Gastrointestinal and Hepatology Diseases, Faculty of Medicine, Suez University, Egypt

Email

frageh2002@hotmail.com

City

Suez

Orcid

-

First Name

Walaa

Last Name

Abd El Gawad

MiddleName

-

Affiliation

Department of Pathology, Faculty of Medicine, Suez University, Suez, Egypt

Email

-

City

-

Orcid

-

First Name

Nermine

Last Name

Nosseir

MiddleName

S

Affiliation

Department of Anatomy, Faculty of Medicine, Suez University, Suez, Egypt

Email

-

City

-

Orcid

-

First Name

Mariam

Last Name

Hassan

MiddleName

-

Affiliation

Department of Gastroenterology, Ismailia Teaching Oncology Hospital, Ismailia, Egypt

Email

-

City

-

Orcid

-

Volume

23

Article Issue

1

Related Issue

17184

Issue Date

2020-03-01

Receive Date

2020-10-19

Publish Date

2020-03-01

Page Start

62

Page End

70

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 23_Issue 1_Pages 62-70.pdf

PDF . 512.2kB

Link

https://scumj.journals.ekb.eg/article_119622.html

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https://scumj.journals.ekb.eg/service?article_code=119622

Order

7

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

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Article

Created At

22 Jan 2023