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114649

Intrafamilial Transmission of Hepatitis C Virus among Household Members of Hepatitis C Virus Patients

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Last updated: 22 Jan 2023

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Abstract

Background:Egypt is considered one of the highly endemic countries with Hepatitis C Virus (HCV) infection. Since we are moving into the HCV-free era, it is necessary to acknowledge the most common methods of HCV transmission. Intrafamilial transmission is one important method that hugely contributed to that endemicity. Aim:Our aim is to identify the prevalence of intrafamilial transmission of HCV among household contacts of chronic HCV patients, risk factors, and methods of transmission. Subjects and Methods:In this study, we recruited 807 Household members of 228 chronic HCV patients. Eligible participants were subjected to history taking, clinical examination, and blood testing for HCV antibodies and PCR. Results:We found that HCV infection was more prevalent among older age groups; married; who live in rural residence; and having high crowding index. Among relatives with HCV, parents were the most affected, followed by siblings, then husbands or wives. The longer the duration of contact, the higher the risk of infection. The incidence of HCV infection was significantly higher among patients who did the following activities: Sharing shaving machine and sugar measurement device with HCV-infected family members, sharing towels with family members, and Handshaking/kissing HCV-infected relatives.Conclusions:Intrafamilial transmission of HCV is an undeniable risk factor, which amplified the burden of HCV. Recognition of remarkable modes of intrafamilial transmission would facilitate suppression of infectivity, as a result achieving the ambition of an HCV-free Egypt.

DOI

10.21608/scumj.2020.114649

Keywords

HCV, viral infections, household transmission

Authors

First Name

Mohammad

Last Name

Tolba

MiddleName

F

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt

Email

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City

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Orcid

-

First Name

Adel

Last Name

Hassan

MiddleName

A

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Mahmoud

Last Name

Sheded

MiddleName

-

Affiliation

Department of Infectious, Gastrointestinal and Hepatology Diseases, Faculty of Medicine, Suez University, Egypt

Email

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City

-

Orcid

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First Name

Fatma

Last Name

Moussa

MiddleName

-

Affiliation

Department of Infectious, Gastrointestinal and Hepatology Diseases, Faculty of Medicine, Suez University, Egypt

Email

frageh2002@hotmail.com

City

Suez

Orcid

-

Volume

23

Article Issue

1

Related Issue

17184

Issue Date

2020-03-01

Receive Date

2020-09-23

Publish Date

2020-03-01

Page Start

15

Page End

22

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 23_Issue 1_Pages 15-22.pdf

PDF . 375.8kB

Link

https://scumj.journals.ekb.eg/article_114649.html

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https://scumj.journals.ekb.eg/service?article_code=114649

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Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

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Article

Created At

22 Jan 2023