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57471

A Study Comparing Chemical Peeling using Trichlo-roacetic Acid and Jessner’s Solution in the Treat-ment of Melasma

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Last updated: 22 Jan 2023

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Abstract

Background: Melasma is a symmetric progressive hyperpigmentation of the facial skin. TCA and Jessner's peel solution are the most popular peeling agents used andmost commonly used for superficial and medium depth peels.Aim: is to compare the efficacy and complications of both Trichloroacetic acid 25% and Jessner's peel solution in the treatment of melasma. Methods: Our study included 29 patients with melasma. Patients were subjected to wood's light to determine the melasma type as the epidermal melasma were included in this study. Split face approach was used as TCA was applied on the right side of the face, and standard jessner's solution was applied on the left side of the face. Every patient had pre peeling preparation period of 2 weeks, sessions were carried out every 2 weeks (each patient had 6 sessions and was followed-up for 3 months). Melasma Area and Severity Index (MASI) were used for clinical evaluation. MASI was recorded in the first visit (baseline score), at the end of the sessions and after the follow up period. Results: There were no statistically significant differences between the two studied methods of treatment regarding degree of improvement according to physicians, patients or blinded observer (p>0.05). Also, there were no statistically significant difference between both studied methods of treatment regarding mean MASI score at baseline (p>0.05). TCA treated side showed highly significant lower mean MASI score after the end of sessions than Jessner's solution treated side (4.9±2.7 vs. 5.5±2.7) (p<0.01). Conclusion: Our findings suggest that either TCA or Jessner's solution can be effectively used to treat melasma.  

DOI

10.21608/scumj.2011.57471

Keywords

TCA, Jessner’s solution, Melasma

Authors

First Name

Moustafa

Last Name

Eyada

MiddleName

M

Affiliation

Department of Dermatology & Venereology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

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Orcid

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First Name

Rabie

Last Name

Abo bakr

MiddleName

A

Affiliation

Department of Dermatology & Venereology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

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Orcid

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First Name

Shereen

Last Name

El-Saman

MiddleName

F

Affiliation

Department of Dermatology & Venereology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

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Orcid

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First Name

Rania

Last Name

Abd El-Naby

MiddleName

A

Affiliation

Department of Dermatology & Venereology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

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Orcid

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Volume

14

Article Issue

1

Related Issue

7461

Issue Date

2011-03-01

Receive Date

2019-11-07

Publish Date

2011-03-01

Page Start

22

Page End

30

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 14_Issue 1_Pages 22-30.pdf

PDF . 278.6kB

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https://scumj.journals.ekb.eg/article_57471.html

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https://scumj.journals.ekb.eg/service?article_code=57471

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Original Article

Type Code

938

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Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

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Article

Created At

22 Jan 2023