Programmed Necrosis-mediated Cell Death and Disease: Recent Advances - Egyptian Knowledge Bank

45311

Programmed Necrosis-mediated Cell Death and Disease: Recent Advances

Article

Last updated: 22 Jan 2023

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Abstract

Cell death classification has been based on morphological characteristics for decades. Modern advances in molecular technology enabled us to explore cell death pathways on a level of unprecedented detail. While necrosis has been considered a negative unpreventable form of cell death, recent findings demonstrate that a subtype of necrosis, namely necroptosis, is a regulated programmed process. Hence, therapeutic intervention to inhibit necroptosis-mediated loss of cells in a disease process is possible. This review highlights recent advances in programmed necrosis (necroptosis) and its potential relationship to human disease.

DOI

10.21608/scumj.2014.45311

Keywords

Necroptosis, programmed cell death, necrosis, caspase-independent cell death

Authors

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First Name

Maged

Last Name

Harraz

MiddleName

Affiliation

Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

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Orcid

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Article Issue

Related Issue

6817

Issue Date

2014-03-01

Receive Date

2019-08-20

Publish Date

2014-03-01

Page Start

Page End

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 17_Issue 1_Pages 1-9.pdf

PDF . 191.9kB

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https://scumj.journals.ekb.eg/article_45311.html

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https://scumj.journals.ekb.eg/service?article_code=45311

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Publication Title

Suez Canal University Medical Journal

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https://scumj.journals.ekb.eg/

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