Aim: To three-dimensionally evaluate the facial harmony in orthodontic patients with vertical growth pattern. Materials and Methods: Cone-beam computed tomography (CT) scans were obtained in 10 normal occlusion adults (4 men, 6 women) with vertical growth pattern, and reconstructed into 3- dimensional (3D) models by using a 3D image software. 3D position of 12 hard tissue landmarks, 3 midlines and 9 pairs of bilateral landmarks, were identified in 3D coordination system, and theirright and left differences were calculated and analyzed. Results: The right and left difference values derived from the study indicated a degree of facial asymmetry in the vertical growers. The lateralramal inclination was the most asymmetric value. Conclusions: A degree of facial asymmetry exists in the vertical growers. The lateral ramal inclination is a significant parameter in the assessment of facial asymmetry in the vertical growers. Facial asymmetry tends to increase according to the lower and lateral positioning of the landmarks in the face. There is a tendency towards left-side dominance.