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65381

Pattern of Endoscopic Esophageal Findings in Relation to Helicobacter Pylori Infection and Histopathology: A Single Center Experience

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Last updated: 04 Jan 2025

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Abstract

Background: Dyspepsia is a common complain among people suffering from gastrointestinal diseases. Few researches investigated the underlying causes in detail. H. Pylori is considered a major finding in patients with dyspepsia and diagnosed with gastrointestinal diseases. Aim: The aim of this study is to determine the pattern of Endoscopic Esophageal lesion in Relation to H. Pylori infection and histopathological features of esophageal and gastric mucosal biopsies in dyspeptic patients eligible for upper GIT Endoscopy. Patients and Methods: all the patients presented with dyspeptic symptoms and were eligible for upper GIT endoscopy during the period from January 2016 to January 2019were included (n=60). Using endoscopy, gastric biopsies were taken for H. Pylori examination and esophageal lesions biopsies were taken for histopathological examination (n=120 specimens). Results: the prevalence of H. pylori among patients with dyspepsia was 81.7%. The most common endoscopic esophageal pattern with H. pylori was erythema and abnormal vascular pattern (67.3%). Reflux esophagitis was the most common Histopathological finding in H. Pylori positive patients (57.1%). Chronic non-specific esophagitis was higher in H. Pylori negative (9.1%) compared with H. Pylori positive (8.2%). Adenocarcinoma was found in 16.3% of H. Pylori positive patients, however, squamous cell carcinoma was more in H. Pylori negative (27.3%) than H. Pylori positive (6.1%). Conclusion: The majority of patient with dyspepsia has H. Pylori infection. Risk factors for malignant esophageal lesions are old age, male gender, smoking and H. pylori infection  

DOI

10.21608/scumj.2019.65381

Keywords

Esophagitis, Adenocarcinoma, Squamous cell carcinoma, Helicobacter pylori

Authors

First Name

Fatma

Last Name

Moussa

MiddleName

R

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez University, Egypt

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Orcid

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First Name

Walaa

Last Name

Abd El Gawad

MiddleName

-

Affiliation

Department of Pathology, Faculty of Medicine, Suez University, Egypt

Email

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City

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Orcid

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First Name

Nermine

Last Name

Nosseir

MiddleName

S

Affiliation

Department of Anatomy, Faculty of Medicine, Suez University, Egypt

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Volume

22

Article Issue

1

Related Issue

6743

Issue Date

2019-03-01

Receive Date

2019-12-16

Publish Date

2019-03-01

Page Start

85

Page End

94

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 22_Issue 1_Pages 85-94.pdf

PDF . 466.4kB

Link

https://scumj.journals.ekb.eg/article_65381.html

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https://scumj.journals.ekb.eg/service?article_code=65381

Order

11

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Pattern of Endoscopic Esophageal Findings in Relation to Helicobacter Pylori Infection and Histopathology: A Single Center Experience

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Article

Created At

22 Jan 2023