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Four Hours Post Endoscopic Retrograde Cholangiopancreatography Serum Amylase as A predictor for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis

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Last updated: 04 Jan 2025

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Abstract

Background: Endoscopic retrograde cholangiopancreatography, uses a combination of both endoscopy and fluoroscopy for diagnosis and treatment of hepatobiliary disorders. ERCP is generally considered to be safe and effective. Post-ERCP complication rates vary widely depending on the complexity of the intervention and the individual patient. Acute pancreatitis is the most common complication following ERCP maneuver, which is reported to occur in 2–10% of patients overall (varying between 2–4% in low risk patients up to 8–40% in high-risk patients). Aim: The study is designed to evaluate the clinical significance of 4-hour post endoscopic retrograde cholangiopancreatography amylase level as an early predictor of post ERCP pancreatitis. This will help to decide when to admit or discharge patient following ERCP, to early diagnose and treat post ERCP pancreatitis and hence spare major hospital resources. Patients and Methods: This study is a prospective cohort study, conducted in theendoscopy unit in Suez Canal university hospital, including adult patients of both sexes eligible for ERCP, excluding patients with pre ERCP pancreatitis, previous ERCP or patients with renal failure. Results: Thisstudy included 86 patients candidate for ERCP of whatever indication excluding patients with pre-endoscopic pancreatitis. In this study pancreatitis occurred in 14 patients out of 86(16.3%).4 hours serum amylase level was significantly higher in patients with post ERCP pancreatitis than in patients without post ERCP pancreatitis (P=0.001). 4hours post ERCP serum amylase is a significant predictor for early prediction of occurrence of PEP. Conclusions: Rising of serum amylase 4 hours post endoscopic retrograde cholangiopancreatographyabove 3.5 ULR is a significant predictor and patient with this level should be admitted and early treated
 

DOI

10.21608/scumj.2019.44515

Keywords

ERCP, pancreatitis, amylase

Authors

First Name

Mohamed

Last Name

Hassan

MiddleName

F

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

Eda

MiddleName

M

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

Abdo

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Suez Canal University, Egypt

Email

d_m.abdo2014@yahoo.com

City

-

Orcid

-

First Name

Bassam

Last Name

Salama

MiddleName

M

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

Volume

22

Article Issue

1

Related Issue

6743

Issue Date

2019-03-01

Receive Date

2019-08-10

Publish Date

2019-03-01

Page Start

38

Page End

45

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 22_Issue 1_Pages 38-45.pdf

PDF . 407.8kB

Link

https://scumj.journals.ekb.eg/article_44515.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=44515

Order

5

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Four Hours Post Endoscopic Retrograde Cholangiopancreatography Serum Amylase as A predictor for Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis

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Type

Article

Created At

22 Jan 2023