Background: HBV is a common major health problem in Egypt and world-wild with burden on nationalhealth care system. The association betweenHBV infection and type 2 diabetes mellitus (T2DM) has been reported over the past decade. However, the relationship between HBV infection and T2DM remains controversial. Aim: to study the prevalence of diabetes mellitus among hepatitis B patients in Suez, Egypt. Patients and Methods: the study included 216 HBV infected patients who attend for regular follow-up in the communicable disease research and training center-Suez city, Egypt. Medical information was collected from patients' medicalrecord. Results: the prevalence of Diabetes among HBV patients was 20.4 %. About 29.6 % of HBV patients had liver cirrhosis, and 4.6% had HCC. The majority (54.54 %) of patients having both HBV and DM weremales. Conclusion:DMis a common medical condition in patients withHBV.