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43543

Assessment of Adrenal Function in Cirrhotic Patients with Spontaneous Bacterial Peritonitis

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Last updated: 22 Jan 2023

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Abstract

Background: One of the subjects that has become a big issue in recent years is adrenal Insuffi-ciency in cirrhotic patients, it is evidenced that there is an argument association between cir-rhotic patients with spontaneous bacterial peritonitis and adrenocortical dysfunction. Aim: to assess adrenal function in chronic liver disease patients with spontaneous bacterial peritonitis to measure hepato-adrenal syndrome problem in our patients. Subjects and Methods: cross sectional analytic study was carried out including 160 persons divided into 4 groups, 40 pa-tients for each. Group1(healthy or control group), Group2 (Patients with compensated liver disease), Group 3 (patients with cirrhotic liver disease and sterile ascites and Group 4( patients with cirrhotic liver disease and spontaneous bacterial peritonitis), Then serum cortisol level was assessed for each group at 8a.m , 8p.m and post synacthen test then the comparison was held to assess adrenal function among them. Results: Our study revealed statistically signifi-cant differences between the comparative groups with pre and post synacthen test where adrenal insufficiency was clear. P-value was (0.001), mean value of total neutrophilic count (p=<0.001), relation between adrenal insufficiency and Child-Pugh score (p= <0.001). Conclu-sion: Spontaneous bacterial peritonitis plays a very major role in adrenal insufficiency.

DOI

10.21608/scumj.2018.43543

Keywords

Adrenal function, Liver cirrhosis, peritonitis

Authors

First Name

Iman

Last Name

Fahmy

MiddleName

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Affiliation

Department of Internal Medicine, Suez Canal University, Egypt

Email

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City

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Orcid

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First Name

Khalil

Last Name

A. Khalil

MiddleName

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Affiliation

Department of Internal Medicine, Suez Canal University, Egypt

Email

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City

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Orcid

-

First Name

Mohmad

Last Name

Sheir

MiddleName

-

Affiliation

Department of Internal Medicine, Suez Canal University, Egypt

Email

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City

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Orcid

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First Name

Basma

Last Name

Badr EL-Dein

MiddleName

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Affiliation

Department of Clinical Pathology, Port Said University

Email

basmabdr@yahoo.com

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-

Orcid

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Volume

21

Article Issue

2

Related Issue

6670

Issue Date

2018-10-01

Receive Date

2019-08-01

Publish Date

2018-10-01

Page Start

107

Page End

112

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 21_Issue 2_Pages 107-112.pdf

PDF . 230.2kB

Link

https://scumj.journals.ekb.eg/article_43543.html

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https://scumj.journals.ekb.eg/service?article_code=43543

Order

7

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

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Article

Created At

22 Jan 2023