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42461

Occupational Risk of Hepatitis B Virus Exposure: Overview and Recommendations

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Last updated: 04 Jan 2025

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Abstract

Hepatitis B Virus has been recognized as an important occupational risk for health-care personnel (HCP) as the virus remains infectious for prolonged periods on environmental surfaces and is transmissible even in the absence of visible blood. Health care personnels (HCPs) who are in contact with blood or body fluids should be vaccinated against hepatitis B. HepB vaccine should administered intramuscularly into the deltoid muscle on a 0, 1, and 6-month schedule followed by HBsAb titre measurement. The protective level of anti-HBs should be ≥ 10mIU/mL. Booster doses of hepatitis B vaccine are not necessary, and periodic serologic testing to monitor antibody concentrations after completion of the vaccine series is not recommended. Hepatitis B immune globulin (HBIG) provides passive anti-HBs and temporary protection lasts for 3-6 months and can be used together with HepB vaccine for postexposure prophylaxis. Vaccinated HCPs who have written documentation of a complete HepB vaccine series (≥ 3 doses) with documented anti-HBs ≥10mIU/mL, are immune and not in need for specific post exposure measures for HBV, whatever the source patient's HBsAg status.

DOI

10.21608/scumj.2018.42461

Keywords

Hepatitis B virus, HBsAg, HbsAb, Vaccination, Post-exposure prophylaxis

Authors

First Name

Nader

Last Name

Nemr

MiddleName

-

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt

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Orcid

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First Name

Rania

Last Name

Kishk

MiddleName

-

Affiliation

Department of Microbiology and Immunology, Faculty of Medicine, Suez Canal University, Egypt

Email

rankishk@yahoo.com

City

-

Orcid

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First Name

Mohamed

Last Name

Mandour

MiddleName

A

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Egypt

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City

-

Orcid

-

First Name

Mostafa

Last Name

Ragheb

MiddleName

-

Affiliation

Department of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Egypt

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Volume

21

Article Issue

2

Related Issue

6670

Issue Date

2018-10-01

Receive Date

2019-07-27

Publish Date

2018-10-01

Page Start

59

Page End

70

Print ISSN

1110-6999

Online ISSN

2090-2581

Article File

SCUMJ_Volume 21_Issue 2_Pages 59-70.pdf

PDF . 379.6kB

Link

https://scumj.journals.ekb.eg/article_42461.html

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https://scumj.journals.ekb.eg/service?article_code=42461

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Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Occupational Risk of Hepatitis B Virus Exposure: Overview and Recommendations

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Article

Created At

22 Jan 2023