Nanoparticles (NPs)are defined as the science and engineering involved in the design, synthesis, characterization and application of materials and devices whose smallest functional organization ranging between 1-100 nm in at least one dimension It is the study of materials at the nanoscale. Nanomaterials are best referred to as particles. NTrefers to the ability to measure, manipulate and organize matter at the nanoscale level. The scale classically refers to matter in the size range of 1–100 nm, but it is often extended to include materials below 1 μm in size .It has the potential to revolutionize veterinary medicine, animal health and other areas of animal production. (25, 20, 7, 39). NT is the design, characterization, production and applications of structures, devices and systems by controlling shape and size at nanometer scale (6). NT is the science and technology of small things (<100 nm) with new changes in their chemical and physical structure, and also higher reactivity and solubility. Nanostructures are outfitted with smart particles to allow their delivery outside certain biologic barriers such as the brain, skin, eye, mucus, blood, cellular, extracellular matrix placenta, and subcellular organelles. (42). NT holds promise for animal health, veterinary medicine, and some areas of animal production. Nanomedicines against various pathogens in veterinary medicine could be developed. Especially, natural nanoantimicrobials such as nano-propolis are useful to veterinary medicine in terms of health, performance, and reliable food production. (40).Veterinary technology has generally established itself well in companion-animal and mixed-animal veterinary medical practice . (9).